Professor
Duke University
Durham, North Carolina
Xinnian Dong is a Professor of Biology at Duke University recognized for her pioneering work in understanding the plant immune mechanisms, particularly an inducible plant immune response known as systemic acquired resistance (SAR). Her lab identified the signaling pathway involved in the perception and the transduction of the SAR signal, salicylic acid, more recently, discovered surprising connections between plant defense with the circadian clock and with the DNA repair machinery. After received her B.S. degree in microbiology from Wuhan University in 1982, Dong came to the US as a graduate student and received her Ph.D. degree in molecular biology from Northwestern University in 1988. She became interested in using Arabidopsis thaliana as a model organism to study plant immune mechanisms when she was a postdoctoral fellow at Massachusetts General Hospital. Dong joined the faculty at Duke University in 1992. She is currently an HHMI-GMBF investigator
(1) Wang, S., Gu, Y., Zebell, S. G., Anderson, L. K., Wang, W., Mohan, R., Dong, X. (2014) A Noncanonical Role for the CKI-RB-E2F Cell-Cycle Signaling Pathway in Plant Effector-Triggered Immunity, Cell Host & Microbe vol. 16:787 - 794
(2) Yan, S.,Wang, W., Marques, J., Mohan, R., Saleh, A., Durrant, W.E., Song, J., Dong, X. (2013). Salicylic Acid Activates DNA Damage Responses to Potentiate Plant Immunity, Molecular Cell 52: 602-610.
(3) Fu, Z.Q., Yan, S., Saleh, A., Wang, W., Ruble, J., Oka, N., Mohan, R., Spoel, S. H., Tada, Y., Zheng, N., and Dong, X., (2012) NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants Nature. 486: 228–232.
(4) Wang, W., Barnaby, J. Y., Tada, Y., Li, H., Tor, M., Caldelari, D., Lee, D.-u. Fu, X.-D. and Dong, X., (2011) Timing of plant immune responses by a central circadian regulator. Nature 470:110-114
Award Talk- Hales Award: Signal transduction in systemic acquired resistance
Wednesday, August 9, 2023
12:00 PM – 12:30 PM EDT