Associate Professor
Purdue University
west Lafayette, Indiana
Dr. Yoon's lab at Purdue University's Department of Botany and Plant Pathology focuses on understanding the molecular mechanisms of plant hormone ethylene signaling in Arabidopsis thaliana. The lab investigates the role of CTR1, a Raf-like protein kinase acting as a negative regulator in the ethylene pathway. Ethylene perception occurs through receptors in the Endoplasmic Reticulum (ER). CTR1 phosphorylates EIN2, blocking its activation in the absence of ethylene. However, upon exposure to ethylene, inactive CTR1 fails to phosphorylate EIN2, leading to its cleavage and the release of a C-terminal domain into the nucleus. This activates the transcription factor EIN3, regulating ethylene-mediated gene expression. The lab seeks to understand the mechanism that regulates the ethylene response induced by EIN2 in the nucleus and explore other roles of CTR1 beyond EIN2 phosphorylation at the ER. Yoon Lab employs diverse techniques like biochemistry, genetics, cell biology, and molecular biology for their research.
Sunday, August 6, 2023
3:45 PM – 3:48 PM EDT
(CS-9-1) Ethylene-triggered subcellular trafficking of CTR1 enhances the response to ethylene gas
Sunday, August 6, 2023
3:48 PM – 4:08 PM EDT