Body of Abstract: Plant productivity is adversely affected by exposure to abiotic stresses including salinity. Leaf tissue undergoes accelerated senescence with exposure to salt stress conditions, culminating in lowered efficiency of photosynthetic machinery. The N6-adenine derivative phytohormone Cytokinin (CK) is well known to delay natural leaf senescence by maintaining functioning photosynthesis processes. How various forms of CK function to control this activity and alter physiological and molecular responses under salt-induced leaf senescence is still not known. Here the CKs, trans-Zeatin (tZ) and its N-glucosylated (tZNGs) forms; tZ7G and tZ9G, were tested for their ability to delay leaf senescence in Arabidopsis thaliana. A modified dark-induced leaf senescence CK bioassay was used to study the photosynthesis performance and transcriptome level changes in detached leaves, across different phases of salt-induced leaf senescence from 2h-72h. Treatments with different CK forms (tZ, tZ7G, and tZ9G) were examined and analyzed effects on photosystem II (PSII) efficiency or Fv/Fm and RNA-sequencing respectively. Our study showed that in the terminal phase of salt-induced leaf senescence, tZ and tZ7G improved PSII efficiency, indicating that these CK forms can both delay senescence. At the transcript level, tZ, tZ7G, and tZ9G revealed differential gene expression across both developmental and salt-induced senescence. Additionally, we found that tZNGs uniquely regulate crucial biological processes including CK signaling compared to tZ.