Biomolecular condensate formation has emerged as a new subcellular organization principle in living cells. In this talk, I will give an overview of ongoing research that begins to implicate biomolecular condensate formation as a potential regulatory mechanism in plant-microbe interactions. In our own study to understand how elevated temperature affects the production of salicylic acid (SA), a central plant defense hormone, we found that formation of GUANYLATE BINDING PROTEIN-LIKE 3 (GBPL3) defense-activated biomolecular condensates (GDACs) in Arabidopsis thaliana is negatively affected at 28 °C compared to at 23 °C. in particular, a key component of the GDAC, MED15, forms condensates in a temperature-dependent manner in Arabidopsis, Nicotiana benthamiana and Escherichia coli. The altered GDAC formation is linked to impaired recruitment of the transcription machinery to the promoters of CBP60g and SARD1, which encode master immune transcription factors. CBP60g and SARD1 transcription was found to be rate-limiting at 28oC for the production of SA, a finding that enabled us to optimize CBP60g transcription to bypass the temperature-vulnerability of SA production, resulting in restoration of SA production and temperature-resilient basal and effector-triggered immunity. These results illustrate an example in which how basic knowledge of biomolecular condensate formation and temperature-sensitivity of the plant immune system can be used to improve plant immune resilience in the context of changing abiotic environments.